Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657543 | 0.88 | KDM4E (0.46) | MAPK1IRAK4KDM4EGAAMAPT | |
| SCHEMBL20345722 | 0.88 | KDM4E (0.46) | MAPK1IRAK4KDM4EGAAMAPT | |
| SCHEMBL4801331 | 0.87 | MAPK1 (0.45) | MAPK1IRAK4KDM4EGAAMAPT | |
| SCHEMBL1341748 | 0.85 | KDM4E (0.56) | KDM4EGAAMAPTTP53CYP3A4 | |
| SCHEMBL27276326 | 0.85 | KDM4E (0.51) | MAPK1KDM4EGAAMAPTTP53 | |
| SCHEMBL2361893 | 0.83 | KDM4E (0.59) | KDM4EGAAMAPTTP53CYP3A4 | |
| SCHEMBL18960381 | 0.83 | TDP1 (0.41) | MAPK1HDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL15830061 | 0.82 | MAPK1 (0.46) | MAPK1IRAK4SYKSMN1; SMN2PDE10A | |
| SCHEMBL12928092 | 0.81 | KDM4E (0.40) | MAPK1HDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL1519326 | 0.81 | KDM1A (0.41) | MAPK1IRAK4HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |