Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638103 | 0.88 | ALOX15 (0.47) | ALOX15KDM4EGAAMAPTTDP1 | |
| SCHEMBL4801338 | 0.87 | MAPK1 (0.45) | MAPK1IRAK4ALOX15KDM4EGAA | |
| SCHEMBL14051378 | 0.83 | MAPT (0.59) | ALOX15KDM4EGAAMAPTTDP1 | |
| SCHEMBL29791971 | 0.81 | AAK1 (0.44) | MAPK1IRAK4ALOX15KDM4EGAA | |
| SCHEMBL2687892 | 0.81 | AAK1 (0.44) | MAPK1IRAK4ALOX15KDM4EGAA | |
| SCHEMBL169734 | 0.81 | MAPK1 (0.45) | MAPK1IRAK4SYKSMN1; SMN2BACE1 | |
| SCHEMBL17675692 | 0.81 | MAPK1 (0.45) | MAPK1IRAK4ALOX15KDM4EGAA | |
| SCHEMBL171321 | 0.81 | MAPK1 (0.45) | MAPK1IRAK4SYKSMN1; SMN2 | |
| SCHEMBL15830061 | 0.79 | MAPK1 (0.46) | MAPK1IRAK4SYKSMN1; SMN2ALDH1A1 | |
| SCHEMBL7178365 | 0.77 | KDM4E (0.47) | MAPK1IRAK4ALOX15KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |