Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055865 | 0.85 | ALDH1A1 (0.45) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL8442402 | 0.80 | TSHR (0.40) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL6690642 | 0.80 | TSHR (0.47) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL4801466 | 0.77 | TSHR (0.44) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL237655 | 0.77 | TSHR (0.44) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL28515424 | 0.76 | TSHR (0.50) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL9493266 | 0.72 | TSHR (0.46) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL28929083 | 0.72 | TSHR (0.46) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL14293603 | 0.72 | ESR1 (0.39) | TSHRTRPA1LMNAALDH1A1HPGD | |
| SCHEMBL4797019 | 0.72 | TSHR (0.39) | TSHRTRPA1LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332552-B2 | Low odor chain transfer agents for controlled radical polymerization | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070088140-A1 | Low odor chain transfer agents for controlled radical polymerization | RENSSELAER POLYTECHNIC INSTITUTE | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088140-A1 | Low odor chain transfer agents for controlled radical polymerization | TAS2R43, CBR3, OR10J3 | TSHR 2315/4885TRPA1 81/4885LMNA 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.