Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660724 | 0.84 | HTT (0.65) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3662392 | 0.82 | HTT (0.72) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL28047855 | 0.82 | NPC1 (0.62) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3662822 | 0.81 | HTT (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3658608 | 0.81 | HTT (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3663202 | 0.81 | HTT (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3658080 | 0.81 | HTT (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3660499 | 0.81 | HTT (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL9114685 | 0.81 | NPC1 (0.57) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL19248913 | 0.81 | PDE4B (0.59) | NPC1RAB9AHPGDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |