⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502217 | 0.89 | — | — | |
| SCHEMBL502218 | 0.89 | — | — | |
| SCHEMBL4840218 | 0.87 | — | — | |
| SCHEMBL4840214 | 0.87 | — | — | |
| SCHEMBL4798081 | 0.87 | FPR3 (0.38) | — | |
| SCHEMBL4848494 | 0.87 | — | — | |
| SCHEMBL4801304 | 0.87 | — | — | |
| SCHEMBL4800130 | 0.83 | — | — | |
| SCHEMBL502921 | 0.79 | FPR3 (0.33) | — | |
| SCHEMBL387446 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375237-B2 | Pyrrolizine compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20060052434-A1 | Pyrrolizine compounds useful as anti-inflammatory agents | CEREP S.A. (FR) | 2006-03-09 | — | — | US | disclosed |