Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124384 | 1.00 | APP (0.60) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12124388 | 0.97 | APP (0.55) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12385268 | 0.97 | APP (0.63) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12124355 | 0.87 | GRM5 (0.48) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12124335 | 0.87 | GRM5 (0.48) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12124330 | 0.87 | GRM5 (0.48) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL17770824 | 0.84 | CYP1A2 (0.59) | APPMAPTGRM5FFAR1NPC1 | |
| SCHEMBL18175861 | 0.83 | APP (0.41) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL12879524 | 0.81 | ESR1 (0.43) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL103830 | 0.81 | ESR1 (0.43) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745113-B1 | NOVEL MATERIAL MIXTURES FOR USE IN ELECTROLUMINESCENCE | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |
| EP-2411501-B1 | APPARATUS FOR CELL OR TISSUE CULTURE | AGENCY SCIENCE TECH & RES (SG) | 2015-08-05 | — | — | EP | disclosed |
| EP-2411501-A1 | APPARATUS FOR CELL OR TISSUE CULTURE | Agency for Science, Technology and Research (SG) | 2012-02-01 | — | — | EP | disclosed |
| EP-1745086-B1 | ELECTROLUMINESCENT POLYMERS | MERCK PATENT GMBH (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010110754-A1 | APPARATUS FOR CELL OR TISSUE CULTURE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-09-30 | — | — | WO | disclosed |