Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124335 | 1.00 | GRM5 (0.48) | GRM5KCNH2ALDH1A1MEN1MAPT | |
| SCHEMBL12124330 | 1.00 | GRM5 (0.48) | GRM5KCNH2ALDH1A1MEN1MAPT | |
| SCHEMBL12124388 | 0.89 | APP (0.55) | GRM5KCNH2ALDH1A1MEN1MAPT | |
| SCHEMBL12124384 | 0.87 | APP (0.60) | GRM5KCNH2ALDH1A1MEN1MAPT | |
| SCHEMBL480205 | 0.87 | APP (0.60) | GRM5KCNH2ALDH1A1MEN1MAPT | |
| SCHEMBL2454173 | 0.87 | LMNA (0.53) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL987143 | 0.87 | LMNA (0.53) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL12124345 | 0.87 | LMNA (0.53) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL12124367 | 0.87 | LMNA (0.53) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL7265559 | 0.87 | LMNA (0.53) | ALDH1A1MEN1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058790-B2 | Material mixtures for use in electroluminescence | MERCK PATENT GMBH (DE) | 2011-11-15 | — | — | US | disclosed |
| US-20070231598-A1 | Electroluminescent Polymers | MERCK PATENT GMBH PATENT & SCIENTIFIC INFORMATION (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070176147-A1 | Novel material mixtures for use in electroluminescence | MERCK PATENT GMBH (DE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070231598-A1 | Electroluminescent Polymers | MAP1LC3C, LAS1L, PARG | GRM5 1300/4885KCNH2 414/4885ALDH1A1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.