Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742671 | 0.91 | ADRB2 (0.38) | ADRB2ADRB1DRD3 | |
| SCHEMBL4738450 | 0.89 | ADRB2 (0.35) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL4738388 | 0.85 | ADRB2 (0.36) | ADRB2 | |
| SCHEMBL4751870 | 0.85 | ADRB2 (0.35) | ADRB2 | |
| SCHEMBL4740671 | 0.81 | ADRB2 (0.48) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL4786393 | 0.81 | ADRB2 (0.35) | ADRB2ADRB1DRD3 | |
| SCHEMBL4738431 | 0.81 | ADRB2 (0.37) | ADRB2 | |
| SCHEMBL4786013 | 0.80 | ADRB2 (0.37) | ADRB2 | |
| SCHEMBL4787047 | 0.76 | ADRB2 (0.32) | ADRB2 | |
| SCHEMBL4739323 | 0.75 | ADRB2 (0.31) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |