Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17963291 | 0.90 | KMT2A (0.71) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17982563 | 0.84 | NR3C1 (0.76) | KMT2ANR3C1 | |
| SCHEMBL17963407 | 0.81 | NR3C1 (0.72) | KMT2ANR3C1 | |
| SCHEMBL587425 | 0.81 | PDE4B (0.60) | KMT2ANR3C1GAASMN1; SMN2MAPT | |
| SCHEMBL17982132 | 0.80 | KMT2A (0.59) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17963410 | 0.80 | NR3C1 (0.73) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17982108 | 0.80 | KMT2A (0.59) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17982529 | 0.80 | KMT2A (0.71) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20413765 | 0.79 | KMT2A (0.67) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17982171 | 0.79 | KMT2A (0.58) | KMT2ANR3C1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075007-A1 | MORPHOLINO-SUBSTITUTED BICYCLOHETEROARYL COMPOUNDS AND THEIR USE AS ANTI CANCER AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |