Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.75 |
| ▸ | KDM5C | P41229 | 8/20 | 0.75 |
| ▸ | KDM4A | O75164 | 6/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.75 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.75 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.75 |
| ▸ | KDM6B | O15054 | 4/20 | 0.75 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.72 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.68 |
| ▸ | KDM4B | O94953 | 3/20 | 0.68 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.66 |
| ▸ | KDM5A | P29375 | 4/20 | 0.63 |
| ▸ | TET3 | O43151 | 1/20 | 0.63 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ASPH | Q12797 | 1/20 | 0.63 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.63 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.63 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29774184 | 1.00 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL29521481 | 1.00 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Hydrochloric Acid SCHEMBL28479928 | 1.00 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL70700 | 0.98 | KDM4C (0.78) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL29407015 | 0.98 | KDM4C (0.78) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL25221788 | 0.95 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL5670010 | 0.95 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL7034221 | 0.95 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL25273097 | 0.95 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Hydrochloric Acid SCHEMBL6018233 | 0.95 | KDM4C (0.75) | KDM4CKDM5CKDM4AKDM4EKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351294-B2 | Surface cleaner | RECKITT BENCKISER (UK) LIMITED (GB) | 2008-04-01 | — | — | US | disclosed |
| US-20060289035-A1 | Photocatalytic; degrading soils; semiconductors; coating surface with a photocatalyst selected from the group consisting of titania and zinc oxide and a ruthenium bi- or ter-pyridyl or phenanthroline-based sensitizer, exposing the surface to visible or infra-red light | MURRER BARRY A | 2006-12-28 | — | — | US | disclosed |
| EP-1240295-B1 | SURFACE CLEANER | RECKITT BENCKISER UK LTD (GB) | 2006-05-17 | — | — | EP | disclosed |
| US-20030171446-A1 | Surface cleaner | RECKITT BENCKISER (UK) LIMITED (GB) | 2003-09-11 | — | — | US | disclosed |
| EP-1240295-A2 | SURFACE CLEANER | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046368-A2 | SURFACE CLEANER | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2001-06-28 | — | — | WO | disclosed |