Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802502 | 0.82 | CYP17A1 (0.31) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3881163 | 0.77 | CYP17A1 (0.35) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3879331 | 0.76 | CYP17A1 (0.36) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3878288 | 0.70 | CYP17A1 (0.38) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3990840 | 0.69 | MKNK1 (0.35) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3886090 | 0.64 | ALDH1A1 (0.45) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3885319 | 0.63 | MKNK1 (0.35) | — | |
| SCHEMBL3874347 | 0.62 | EGFR (0.31) | — | |
| SCHEMBL3878218 | 0.62 | PRKDC (0.38) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3874513 | 0.61 | MKNK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |