Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.70 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803017 | 0.90 | AHR (0.79) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30307425 | 0.88 | AHR (1.00) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30288215 | 0.88 | AHR (1.00) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4797786 | 0.88 | AHR (1.00) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL25877004 | 0.87 | AHR (0.70) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL25876975 | 0.85 | AHR (0.67) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15455636 | 0.85 | KDM4E (0.70) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4807691 | 0.84 | AHR (0.82) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL12471638 | 0.84 | KDM4E (0.66) | AHRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4809936 | 0.84 | AHR (0.60) | AHRMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384966-B2 | 2-arylbenzothiazole derivatives | PHARMINXO LIMITED (GB) | 2008-06-10 | — | — | US | disclosed |
| US-20060063816-A1 | 2-Arylbenzothiazole derivatives | STEVENS MALCOLM F G | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063816-A1 | 2-Arylbenzothiazole derivatives | CX3CR1, HCN2, CYBB | AHR 60/4885MAPT 4559/4885KDM4E 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.