Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677578 | 0.88 | SLC6A4 (0.60) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8341049 | 0.85 | SLC6A4 (0.51) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL7053189 | 0.81 | SLC6A4 (0.71) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL7053107 | 0.79 | SLC6A4 (0.77) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4803498 | 0.77 | SLC6A4 (0.73) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4803492 | 0.77 | SLC6A4 (0.58) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL12047445 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL341802 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL2209541 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL29440242 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166437-A | Process for the preparation of fluoxetine | ORION-YHTYMA OY (FI) | 1992-11-24 | — | — | US | claimed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | claimed |
| US-7390847-B2 | Polymer derivatives for the treatment of metals | BASF SE (DE) | 2008-06-24 | — | — | US | disclosed |
| US-20050121114-A1 | Polymer derivatives for the treatment of metals | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | US | disclosed |
| EP-0391070-B1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION YHTYMAE OY (FI) | 1994-01-19 | — | — | EP | disclosed |
| EP-0391070-B1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION YHTYMAE OY (FI) | 1994-01-19 | — | — | EP | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |