Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053107 | 0.87 | SLC6A4 (0.77) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL7053189 | 0.84 | SLC6A4 (0.71) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4803483 | 0.77 | SLC6A4 (0.62) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8677578 | 0.75 | SLC6A4 (0.60) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL6492110 | 0.74 | SLC6A4 (0.66) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL341802 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Atomoxetine SCHEMBL12047445 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Nisoxetine SCHEMBL3897550 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Nisoxetine SCHEMBL29401038 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Nisoxetine SCHEMBL30026153 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390847-B2 | Polymer derivatives for the treatment of metals | BASF SE (DE) | 2008-06-24 | — | — | US | disclosed |
| US-20050121114-A1 | Polymer derivatives for the treatment of metals | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | US | disclosed |
| EP-0612242-A4 | METHODS AND COMPOSITIONS UTILIZING PURE S(+) ISOMER FLUOXETINE. | SEPRACOR INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0612242-A1 | METHODS AND COMPOSITIONS UTILIZING PURE S(+) ISOMER FLUOXETINE | SEPRACOR, INC. (US) | 1994-08-31 | — | — | EP | disclosed |