Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1234712 | 0.97 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL21087133 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL14770377 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL2944700 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| Adipic Acid SCHEMBL11008725 | 0.90 | AKR1B1 (0.56) | ALDH1A1TSHRLMNAAKR1B1PPARG | |
| SCHEMBL16908570 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL19382679 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL22445105 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL22445118 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 | |
| SCHEMBL17418301 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAEGLN1ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2656880-B1 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B KOLORMAKEUP & SKINCARE S P A (IT) | 2019-05-08 | — | — | EP | claimed |
| US-9265700-B2 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B.KOLORMAKEUP & SKINCARE S.R.L. (IT) | 2016-02-23 | — | — | US | claimed |
| EP-2656880-A2 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B. Kolormakeup & Skincare S.r.l. (IT) | 2013-10-30 | — | — | EP | claimed |
| US-20130236405-A1 | METHOD FOR THE PREPARATION OF COLOURED COSMETIC POWDER PRODUCTS FOR USE ON THE SKIN OF THE EYES, FACE AND BODY | B.KOLORMAKEUP & SKINCARE S.R.L. (IT) | 2013-09-12 | — | — | US | claimed |
| EP-2656880-B1 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B KOLORMAKEUP & SKINCARE S P A (IT) | 2019-05-08 | — | — | EP | disclosed |
| US-9265700-B2 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B.KOLORMAKEUP & SKINCARE S.R.L. (IT) | 2016-02-23 | — | — | US | disclosed |
| EP-2656880-A2 | Method for the preparation of coloured cosmetic powder products for use on the skin of the eyes, face and body | B. Kolormakeup & Skincare S.r.l. (IT) | 2013-10-30 | — | — | EP | disclosed |
| US-20130236405-A1 | METHOD FOR THE PREPARATION OF COLOURED COSMETIC POWDER PRODUCTS FOR USE ON THE SKIN OF THE EYES, FACE AND BODY | B.KOLORMAKEUP & SKINCARE S.R.L. (IT) | 2013-09-12 | — | — | US | disclosed |
| US-7452654-B2 | Toner production method and toner production apparatus | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-20060160012-A1 | Toner production method and toner production apparatus | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. | 2006-07-20 | — | — | US | disclosed |