Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810386 | 0.97 | SIRT2 (0.40) | CYP2C19CYP3A4SIRT2ALDH1A1CYP2C9 | |
| SCHEMBL28043401 | 0.95 | CYP3A4 (0.36) | CYP2C19CYP3A4SIRT2ALDH1A1POLB | |
| SCHEMBL6905227 | 0.95 | SIRT2 (0.43) | CYP2C19CYP3A4SIRT2AKT1 | |
| SCHEMBL4812034 | 0.95 | SIRT2 (0.43) | CYP2C19CYP3A4SIRT2AKT1 | |
| SCHEMBL6907567 | 0.91 | CYP3A4 (0.39) | CYP3A4SIRT2AKT1 | |
| SCHEMBL4811574 | 0.91 | CYP2C19 (0.41) | CYP2C19CYP3A4SIRT2ALDH1A1CYP2C9 | |
| SCHEMBL10477317 | 0.87 | CYP1A2 (0.39) | CYP2C19CYP3A4ALDH1A1CYP2C9TSHR | |
| SCHEMBL11855720 | 0.86 | PRKCA (0.39) | CYP2C19CYP3A4ALDH1A1TSHR | |
| SCHEMBL27123245 | 0.85 | CYP2C19 (0.39) | CYP2C19CYP3A4ALDH1A1CYP2C9TSHR | |
| SCHEMBL29168788 | 0.85 | SIRT2 (0.40) | CYP2C19CYP3A4SIRT2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388103-B2 | Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-20060094843-A1 | Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2006-05-04 | — | — | US | disclosed |
| WO-2006045246-A1 | CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2006-05-04 | — | — | WO | disclosed |
| EP-0755912-B1 | Process for the preparation of 2-substituted cyclopentanones | BAYER AG (DE) | 1999-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094843-A1 | Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof | C5, C1S, AKR1C3 | CYP2C19 75/4885CYP3A4 86/4885SIRT2 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.