Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.96 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.96 |
| ▸ | CNR1 | P21554 | 1/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.85 |
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | TP53 | P04637 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | FAAH | O00519 | 1/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | PPARG | P37231 | 5/20 | 0.72 |
| ▸ | F7 | P08709 | 4/20 | 0.72 |
| ▸ | F3 | P13726 | 4/20 | 0.72 |
| ▸ | PPARD | Q03181 | 4/20 | 0.72 |
| ▸ | PPARA | Q07869 | 4/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469455 | 1.00 | KDM4E (0.96) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL4805185 | 1.00 | KDM4E (0.96) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL10445589 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL18619526 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL571437 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL5905645 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL10445415 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7626693 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL10445407 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL571436 | 0.98 | KDM4E (1.00) | KDM4ESOAT1CNR1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43632-E1 | 1,3-propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-RE40546-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2008-10-21 | — | — | US | disclosed |
| US-RE40480-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA LIMITED (GB) | 2008-09-02 | — | — | US | disclosed |
| US-6555700-B1 | Bioactives (drugs, nutrients) in a form in which they are lipophilic so that they can pass lipid barriers (membranes, skin etc.) in the body readily; glycerides of esterified, aminated or etherified bioactives; side effect reduction | SCOTIA HOLDINGS PLC (GB) | 2003-04-29 | — | — | US | disclosed |
| EP-0823889-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034846-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |