SCHEMBL4805290

SCHEMBL4805290

C=C(C)C(=O)OC(C)CC(C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
TSHR P16473 3/20 0.40
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
GGT1 P19440 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
BLM P54132 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2779922 0.85 ALDH1A1 (0.53) ALDH1A1SCN1ASCN2ASCN3ATSHR
SCHEMBL194452 0.85 ALDH1A1 (0.56) ALDH1A1TSHRALOX15KDM4ETDP1
Phthalic Acid SCHEMBL28346932 0.84 ALDH1A1 (0.48) ALDH1A1SCN1ASCN2ASCN3ATSHR
SCHEMBL36716 0.84 ALDH1A1 (0.48) ALDH1A1TSHRALOX15KDM4EHSD17B10
SCHEMBL696764 0.84 ALDH1A1 (0.51) ALDH1A1TSHRALOX15KDM4EHSD17B10
SCHEMBL7865741 0.84 ALDH1A1 (0.64) ALDH1A1SCN1ASCN2ASCN3ATSHR
SCHEMBL28586017 0.83 ALDH1A1 (0.45) ALDH1A1SCN1ASCN2ASCN3ATSHR
SCHEMBL6900189 0.81 ALDH1A1 (0.45) ALDH1A1TSHRALOX15KDM4EHSD17B10
SCHEMBL8982568 0.81 ALDH1A1 (0.48) ALDH1A1SCN1ASCN2ASCN3ATSHR
SCHEMBL10529298 0.80 ALDH1A1 (0.44) ALDH1A1TSHRALOX15KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120207990-A1 PRODUCTION METHOD OF ANTIREFLECTION FILM, ANTIREFLECTION FILM AND COATING COMPOSITION FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
WO-2008098872-A1 HIGH REFRACTIVE INDEX HARD COAT DSM IP ASSETS B.V. (NL) 2008-08-21 WO disclosed
US-7332216-B2 Film-reinforced glasses BRIDGESTONE CORPORATION (JP) 2008-02-19 US disclosed
EP-1137720-B1 RADIATION-CURABLE METAL PARTICLES AND CURABLE RESIN COMPOSITIONS COMPRISING THESE PARTICLES JSR CORP (JP) 2007-08-22 EP disclosed
EP-1347069-A1 HIGH-STRENGTH SPRING STEEL AND SPRING STEEL WIRE NIPPON STEEL CORPORATION (JP) 2003-09-24 EP disclosed
EP-1346962-A1 FILM-REINFORCED GLASSES BRIDGESTONE CORPORATION (JP) 2003-09-24 EP disclosed
US-20030111159-A1 Film-reinforced glasses BRIDGESTONE CORPORATION (JP) 2003-06-19 US disclosed
US-20030105189-A1 Radiation-curable metal particles and curable resin compositions comprising these particles DSM, N.V., JSR CORPORATION 2003-06-05 US disclosed
US-6528604-B1 For coatings exhibiting excellent scratch resistance, weather resistance, adhesiveness and curability; polymerizable unsaturated group bonded via a silyloxy group DSM N.V. (NL) 2003-03-04 US disclosed
US-6521677-B2 Radiation transparent; high refractive index DSM N.V. (NL) 2003-02-18 US disclosed
US-6355703-B1 MODIFIED ACRYLATED RESIN DSM N. V. (NL) 2002-03-12 US disclosed
US-20020019461-A1 Radiation-curable metal particles and curable resin compositions comprising these particles JSR CORPORATION (JP) 2002-02-14 US disclosed
EP-1137720-A1 RADIATION-CURABLE METAL PARTICLES AND CURABLE RESIN COMPOSITIONS COMPRISING THESE PARTICLES DSM N.V. (NL) 2001-10-04 EP disclosed
US-6160067-A Reactive silica particles, process for manufacturing the same, use of the same DSM N.V. (NL) 2000-12-12 US disclosed
WO-2000027931-A1 RADIATION-CURABLE METAL PARTICLES AND CURABLE RESIN COMPOSITIONS COMPRISING THESE PARTICLES DSM N.V. (NL) 2000-05-18 WO disclosed
US-6013749-A MIXTURE COMPRISING POLYFUNCTIONAL ACRYLATE ESTER COMPOUND, REACTION PRODUCT OF SILICA PARTICLES COUPLED TO ALKOXYSILANE COMPOUND CONTAINING THIO- OR DITHIOCARBAMATE MOIETIES, AND A SILICONE POLYMER; HARD PROTECTIVE COATINGS DSM N.V. (NL) 2000-01-11 US disclosed
EP-0877777-B1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM NV (NL) 2000-01-05 EP disclosed
EP-0877777-A1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM N.V. (NL) 1998-11-18 EP disclosed
EP-0867469-A2 Liquid curable resin composition DSM N.V. (NL) 1998-09-30 EP disclosed
WO-1997012942-A1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM N.V. (NL) 1997-04-10 WO disclosed