SCHEMBL4805293

SCHEMBL4805293

C=C(C)C(=O)OCCCCCOC(=O)c1ccccc1C(=O)OCCCCCOC(=O)C(=C)C

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.66
ALDH1A1 P00352 7/20 0.66
LMNA P02545 2/20 0.66
CYP3A4 P08684 3/20 0.63
MAPK1 P28482 2/20 0.63
TP53 P04637 1/20 0.63
TDP1 Q9NUW8 5/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
POLB P06746 2/20 0.55
APEX1 P27695 1/20 0.55
HTT P42858 1/20 0.55
HSD17B10 Q99714 2/20 0.54
KDM4E B2RXH2 2/20 0.54
PTGS2 P35354 1/20 0.46
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11229934 1.00 TSHR (0.66) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL2532109 0.98 TSHR (0.65) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL645003 0.95 TSHR (0.62) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL194750 0.92 TSHR (0.58) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL129437 0.92 TSHR (0.62) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL28210542 0.92 TSHR (0.73) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL28996621 0.90 TSHR (0.61) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL31304736 0.89 TSHR (0.55) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL194453 0.89 TSHR (0.55) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL28304537 0.88 TSHR (0.54) TSHRALDH1A1LMNACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120207990-A1 PRODUCTION METHOD OF ANTIREFLECTION FILM, ANTIREFLECTION FILM AND COATING COMPOSITION FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
WO-2008098872-A1 HIGH REFRACTIVE INDEX HARD COAT DSM IP ASSETS B.V. (NL) 2008-08-21 WO disclosed
US-7332216-B2 Film-reinforced glasses BRIDGESTONE CORPORATION (JP) 2008-02-19 US disclosed
EP-1137720-B1 RADIATION-CURABLE METAL PARTICLES AND CURABLE RESIN COMPOSITIONS COMPRISING THESE PARTICLES JSR CORP (JP) 2007-08-22 EP disclosed
EP-1347069-A1 HIGH-STRENGTH SPRING STEEL AND SPRING STEEL WIRE NIPPON STEEL CORPORATION (JP) 2003-09-24 EP disclosed
EP-1346962-A1 FILM-REINFORCED GLASSES BRIDGESTONE CORPORATION (JP) 2003-09-24 EP disclosed
US-20030111159-A1 Film-reinforced glasses BRIDGESTONE CORPORATION (JP) 2003-06-19 US disclosed
US-20030105189-A1 Radiation-curable metal particles and curable resin compositions comprising these particles DSM, N.V., JSR CORPORATION 2003-06-05 US disclosed
US-6528604-B1 For coatings exhibiting excellent scratch resistance, weather resistance, adhesiveness and curability; polymerizable unsaturated group bonded via a silyloxy group DSM N.V. (NL) 2003-03-04 US disclosed
US-6521677-B2 Radiation transparent; high refractive index DSM N.V. (NL) 2003-02-18 US disclosed
EP-0867469-B1 Liquid curable resin composition DSM NV (NL) 2003-02-12 EP disclosed
US-6355703-B1 MODIFIED ACRYLATED RESIN DSM N. V. (NL) 2002-03-12 US disclosed
US-20020019461-A1 Radiation-curable metal particles and curable resin compositions comprising these particles JSR CORPORATION (JP) 2002-02-14 US disclosed
US-6160067-A Reactive silica particles, process for manufacturing the same, use of the same DSM N.V. (NL) 2000-12-12 US disclosed
US-6013749-A MIXTURE COMPRISING POLYFUNCTIONAL ACRYLATE ESTER COMPOUND, REACTION PRODUCT OF SILICA PARTICLES COUPLED TO ALKOXYSILANE COMPOUND CONTAINING THIO- OR DITHIOCARBAMATE MOIETIES, AND A SILICONE POLYMER; HARD PROTECTIVE COATINGS DSM N.V. (NL) 2000-01-11 US disclosed
EP-0877777-B1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM NV (NL) 2000-01-05 EP disclosed
EP-0877777-A1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM N.V. (NL) 1998-11-18 EP disclosed
EP-0867469-A2 Liquid curable resin composition DSM N.V. (NL) 1998-09-30 EP disclosed
WO-1997012942-A1 REACTIVE SILICA PARTICLES, PROCESS FOR MANUFACTURING THE SAME, USE OF THE SAME DSM N.V. (NL) 1997-04-10 WO disclosed