SCHEMBL4806201

SCHEMBL4806201

O=C1c2ccccc2OCC1c1ccc(O)cc1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 19/20 0.77
ALOX12 P18054 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoflavanone SCHEMBL30593548 0.87 CYP19A1 (1.00) CYP19A1
Isoflavanone SCHEMBL15883785 0.87 CYP19A1 (1.00) CYP19A1
Isoflavanone SCHEMBL72983 0.87 CYP19A1 (1.00) CYP19A1
SCHEMBL5797926 0.86 ALOX12 (0.75) CYP19A1ALOX12
SCHEMBL16152440 0.86 ALOX12 (0.75) CYP19A1ALOX12
SCHEMBL131543 0.86 ALOX12 (0.75) CYP19A1ALOX12
SCHEMBL13267880 0.84 CYP19A1 (0.77) CYP19A1
SCHEMBL2854125 0.84 CYP19A1 (1.00) CYP19A1
SCHEMBL13382254 0.84 CYP19A1 (0.77) CYP19A1
SCHEMBL13311871 0.84 CYP19A1 (1.00) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462478-B2 isolated from licorice; catalyzes a dehydration reaction of 2-hydroxy hisoflavanone NIHON UNIVERSITY (JP) 2008-12-09 US disclosed
US-20070050865-A1 Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same NIHON UNIVERSITY (JP) 2007-03-01 US disclosed