Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | EYA2 | O00167 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL17984124 | 0.81 | TDP1 (0.61) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL17183002 | 0.79 | ALDH1A1 (0.58) | TDP1EYA2APPACETSHR | |
| Toluene SCHEMBL7854301 | 0.78 | TSHR (0.55) | TDP1TSHRLMNAALOX12ACHE | |
| SCHEMBL2807141 | 0.78 | TDP1 (0.56) | TDP1EYA2APPACETSHR | |
| Pentetic Acid SCHEMBL10361749 | 0.78 | TDP1 (0.60) | TDP1EYA2APPACETSHR | |
| SCHEMBL2284795 | 0.78 | TDP1 (0.56) | TDP1EYA2APPACETSHR | |
| SCHEMBL12243695 | 0.78 | TDP1 (0.56) | TDP1EYA2APPACETSHR | |
| SCHEMBL12243645 | 0.78 | TDP1 (0.56) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL3810357 | 0.77 | TDP1 (0.88) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL9128547 | 0.77 | TDP1 (0.88) | TDP1EYA2APPACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371360-B2 | Phyllosilicate is subjected to ion exchange with cationic surfactant and, organic intercalate compound is intercalated in phyllosilicate, with the proviso that intercalation of dimethylformamide, chloroform, dimethylacetamide, toluene and dimethylsulfoxide can take place also without prior ion exchange | HILTI AKTIENGESELLSCHAFT (LI) | 2008-05-13 | — | — | US | claimed |
| US-20040183051-A1 | Method for producing phyllosilicate-intercalation compounds, the intercalation compounds thereby obtained and their use | HILTI AKTIENGESELLSCHAFT (LI) | 2004-09-23 | — | — | US | claimed |