SCHEMBL4806948

SCHEMBL4806948

O=C(O)C(=CS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
MCOLN3 Q8TDD5 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
AKR1C1 Q04828 4/20 0.50
AKR1C2 P52895 3/20 0.50
PTGS2 P35354 1/20 0.50
AKR1C3 P42330 3/20 0.46
TLR9 Q9NR96 1/20 0.45
HSD11B1 P28845 2/20 0.44
KMT2A Q03164 1/20 0.42
KAT6A Q92794 1/20 0.41
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8815065 0.80 AKR1C1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL5491917 0.78 CYP2C9 (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL5152628 0.78 AKR1C1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL5491914 0.78 CYP2C9 (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL8915867 0.78 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL28395693 0.76 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL12449526 0.74 CYP2C19 (0.66) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL11738550 0.74 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL11738558 0.74 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL29265117 0.74 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416821-B2 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2008-08-26 US disclosed
EP-1743363-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FujiFilm Electronic Materials USA, Inc. (US) 2007-01-17 EP disclosed
US-20050238997-A1 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2005-10-27 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed