SCHEMBL4807225

SCHEMBL4807225

CCCCC1(C(=O)OCC)CCCC1O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 10/20 0.47
F10 P00742 1/20 0.35
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4807081 0.95 AKT1 (0.51) AKT1F10
SCHEMBL4812035 0.94 AKT1 (0.53) AKT1
SCHEMBL4807372 0.91 AKT1 (0.41) AKT1F10POLBPKMLMNA
SCHEMBL19004893 0.84 AKT1 (0.38) AKT1F10POLBPKMLMNA
SCHEMBL4805601 0.84 F10 (0.38) AKT1F10POLB
SCHEMBL4809127 0.82 AKT1 (0.36) AKT1F10POLBPKMLMNA
SCHEMBL6059855 0.81 AKT1 (0.33) AKT1
SCHEMBL4823840 0.80 AKT1 (0.51) AKT1POLBPKMLMNAMAPT
SCHEMBL4808662 0.79 F10 (0.35) AKT1F10POLB
SCHEMBL27567104 0.77 LMNA (0.51) POLBPKMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008517957-A 2008-05-29 JP claimed
US-20060094843-A1 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 US claimed
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO claimed
US-7388103-B2 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
CN-100348571-C 2-alkoxyl cyclopentyl ester compound, its synthesis method and application CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
CN-100338018-C Cyclopentyl ester analog compound and its synthesis method and uses CHINA PETROLEUM & CHEMICAL (CN) 2007-09-19 CN disclosed
CN-1789234-A 2-alkoxyl cyclopentyl ester compound, its synthesis method and application CHINA PETROLEUM & CHEMICAL (CN) 2006-06-21 CN disclosed
US-20060094843-A1 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 US disclosed
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed
CN-1765871-A Cyclopentyl ester analog compound and its synthesis method and uses CHINA PETROLEUM & CHEMICAL (CN) 2006-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094843-A1 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof C5, C1S, AKR1C3 AKT1 1995/4885F10 1063/4885POLB 1500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.