Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.81 |
| ▸ | CNR1 | P21554 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 3/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807460 | 1.00 | MGLL (0.81) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL8704825 | 1.00 | MGLL (0.81) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL17558128 | 0.98 | MGLL (0.78) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL3660036 | 0.98 | MGLL (0.78) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL3660645 | 0.97 | MGLL (0.86) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL3660643 | 0.97 | MGLL (0.86) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL4812727 | 0.94 | MGLL (0.76) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL11231403 | 0.94 | MGLL (0.76) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL4812731 | 0.94 | MGLL (0.76) | MGLLCNR1ALDH1A1MAPTTHRB | |
| SCHEMBL8017799 | 0.94 | MGLL (0.76) | MGLLCNR1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43632-E1 | 1,3-propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-RE40546-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2008-10-21 | — | — | US | disclosed |
| US-RE40480-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA LIMITED (GB) | 2008-09-02 | — | — | US | disclosed |
| EP-0823897-B1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCARISTA LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-6555700-B1 | Bioactives (drugs, nutrients) in a form in which they are lipophilic so that they can pass lipid barriers (membranes, skin etc.) in the body readily; glycerides of esterified, aminated or etherified bioactives; side effect reduction | SCOTIA HOLDINGS PLC (GB) | 2003-04-29 | — | — | US | disclosed |
| EP-0823889-B1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCARISTA LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| US-6015821-A | SKIN, PSYCHOLOGICAL AND CARDIOVASCULAR DISORDERS; ANTICARCINOGENIC, ANTIINFLAMMATORY AND ANTIDIABETIC AGENTS | SCARISTA LIMITED (IM) | 2000-01-18 | — | — | US | disclosed |
| EP-0823889-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034846-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |