SCHEMBL4807979

SCHEMBL4807979

CCC(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.39
TAAR1 Q96RJ0 1/20 0.35
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP2D6 P10635 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HIF1A Q16665 1/20 0.32
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.32
GRIN1 Q05586 4/20 0.32
GRIN2A Q12879 4/20 0.32
GRIN2D O15399 3/20 0.32
GRIN2C Q14957 3/20 0.32
GRIN2B Q13224 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4808349 0.80 KCNN4 (0.33) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL4815053 0.79 KCNN4 (0.39) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL4815052 0.78 TSHR (0.32) KCNN4TAAR1CYP2C19ALDH1A1TSHR
SCHEMBL4812223 0.77 KCNN4 (0.38) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL8162264 0.75 KCNN4 (0.36) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL4810680 0.75 MAPK1 (0.42) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL4814448 0.73 MAPK1 (0.41) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL28075836 0.73 TAAR1 (0.43) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL4814612 0.73 KCNN4 (0.35) KCNN4TAAR1MAPK1CYP2C19ALDH1A1
SCHEMBL16538512 0.73 TAAR1 (0.43) KCNN4TAAR1MAPK1CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405254-B2 Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane ALBEMARLE CORPORATION (US) 2008-07-29 US disclosed
EP-1711555-B1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORP (US) 2008-07-09 EP disclosed
US-20070117904-A1 Flame Retardant Compositions and Their Use ALBEMARLE CORPORATION (US) 2007-05-24 US disclosed
US-7202296-B2 Flame retardant compositions and their use ALBEMARLE CORPORATION (US) 2007-04-10 US disclosed
EP-1711555-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2006-10-18 EP disclosed
WO-2005063869-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2005-07-14 WO disclosed
US-20050137311-A1 Flame retardant compositions and their use ALBEMARLE CORPORATION 2005-06-23 US disclosed