SCHEMBL4815053

SCHEMBL4815053

BrC(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.39
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
PTPN1 P18031 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812223 0.97 KCNN4 (0.38) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL4812311 0.92 KCNN4 (0.41) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL4808349 0.80 KCNN4 (0.33) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL4952601 0.80 KIF11 (0.41) KCNN4ALDH1A1TSHRMAPK1CYP3A4
SCHEMBL4813388 0.80 CA1 (0.35) KCNN4ALDH1A1TSHRMAPK1
SCHEMBL653357 0.79 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL4810680 0.79 MAPK1 (0.42) KCNN4ALDH1A1TSHRMAPK1TAAR1
SCHEMBL4815052 0.79 TSHR (0.32) KCNN4ALDH1A1TSHRCYP1A2TAAR1
SCHEMBL4807979 0.79 KCNN4 (0.39) KCNN4ALDH1A1TSHRMAPK1TAAR1
SCHEMBL26697300 0.78 ALDH1A1 (0.50) KCNN4ALDH1A1TSHRMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405254-B2 Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane ALBEMARLE CORPORATION (US) 2008-07-29 US disclosed
EP-1711555-B1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORP (US) 2008-07-09 EP disclosed
US-20070117904-A1 Flame Retardant Compositions and Their Use ALBEMARLE CORPORATION (US) 2007-05-24 US disclosed
US-7202296-B2 Flame retardant compositions and their use ALBEMARLE CORPORATION (US) 2007-04-10 US disclosed
EP-1711555-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2006-10-18 EP disclosed
WO-2005063869-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2005-07-14 WO disclosed
US-20050137311-A1 Flame retardant compositions and their use ALBEMARLE CORPORATION 2005-06-23 US disclosed