Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477216 | 1.00 | ALDH1A1 (0.56) | ALDH1A1DHODHTAS1R3TAS1R1HSD17B10 | |
| SCHEMBL4485228 | 0.86 | ALDH1A1 (0.55) | ALDH1A1DHODHHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL4493757 | 0.86 | ALDH1A1 (0.55) | ALDH1A1DHODHHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL4481432 | 0.79 | ALDH1A1 (0.56) | ALDH1A1DHODHHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL4487753 | 0.79 | ALDH1A1 (0.56) | ALDH1A1DHODHHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL4490240 | 0.78 | KCNA5 (0.57) | — | |
| SCHEMBL4484985 | 0.78 | KCNA5 (0.57) | — | |
| SCHEMBL4804977 | 0.78 | KCNA5 (0.57) | — | |
| SCHEMBL4478494 | 0.78 | KCNA5 (0.54) | ALDH1A1TP53POLB | |
| SCHEMBL4804974 | 0.78 | KCNA5 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678130-B1 | AMIDOMETHYL-SUBSTITUTED 2-(4-SULFONILAMINO)-3-HIDROXY-3,4-DIHYDRO-2H-CHROMIUM-6-YL-DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS | SOLVAY PHARM GMBH (DE) | 2008-08-20 | — | — | EP | disclosed |