Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152628 | 0.99 | HSD17B10 (0.42) | HSD17B10ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL4815896 | 0.87 | MAPT (0.47) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6279991 | 0.87 | HSD17B10 (0.43) | HSD17B10ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3147087 | 0.86 | MAPT (0.46) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9263210 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAAMAPK1MEN1KMT2A | |
| SCHEMBL13980917 | 0.72 | CNR1 (0.43) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8785889 | 0.71 | IRAK4 (0.52) | POLBLMNAIRAK4 | |
| SCHEMBL3146828 | 0.71 | CNR1 (0.43) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13478938 | 0.71 | CNR1 (0.43) | HSD17B10ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21820809 | 0.70 | MEN1 (0.48) | ALDH1A1GAAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470793-B2 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-20060155122-A1 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155122-A1 | Thiazol-(bi)cycloalkyl-carboxanilides | MRPL21, Q6ZSR9, QPCT | HSD17B10 1162/4885ALDH1A1 502/4885GAA 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.