⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9114299 | 0.98 | TBXAS1 (0.49) | — | |
| Glutarate SCHEMBL28564870 | 0.88 | TBXAS1 (0.62) | — | |
| SCHEMBL8519473 | 0.83 | TBXAS1 (0.50) | — | |
| Imidazoleacetic Acid SCHEMBL360337 | 0.81 | — | — | |
| SCHEMBL1261468 | 0.81 | — | — | |
| SCHEMBL18985083 | 0.80 | TBXAS1 (0.45) | — | |
| SCHEMBL2787115 | 0.80 | TBXAS1 (0.57) | — | |
| SCHEMBL2648605 | 0.79 | — | — | |
| SCHEMBL3056452 | 0.79 | — | — | |
| SCHEMBL1259774 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606888-B | Pyrrole derivative and preparation method and application thereof | 中国药科大学 | 2023-08-18 | — | — | CN | claimed |
| EP-2285375-A2 | SPIROAZAINDOLES | Merck Sharp & Dohme Corp. (US) | 2011-02-23 | — | — | EP | claimed |
| EP-2170876-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTINTION AND TREATMENT OF RESTENOSIS COMPRISING ISOXAZOLE DERIVATIVES | SK Holdings Co., Ltd. (KR) | 2010-04-07 | — | — | EP | claimed |
| WO-2009137291-A2 | SPIROAZAINDOLES | MERCK & CO., INC. (US) | 2009-11-12 | — | — | WO | claimed |
| WO-2009005269-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTINTION AND TREATMENT OF RESTENOSIS COMPRISING ISOXAZOLE DERIVATIVES | SK HOLDINGS CO., LTD. (KR) | 2009-01-08 | — | — | WO | claimed |
| EP-1971600-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2008-09-24 | — | — | EP | claimed |
| WO-2007078113-A1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2007-07-12 | — | — | WO | claimed |
| US-5512588-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-30 | — | — | US | claimed |
| EP-0174136-A1 | Derivatives of dihydro-1H-pyrrolo(1,2-c)imidazol-3,5-dione as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-03-12 | — | — | EP | claimed |
| US-4079136-A | Imidazolylacetic acid amides, their production, antimycotic compositions comprising said compounds and their use as antimycotic agents | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | claimed |
| US-4033964-A | Imidazolylacetic acid amides, their production, antimycotic compositions comprising said compounds and their use as antimycotic agents | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | claimed |
| US-4032636-A | IMIDAZOLYLACETIC ACID AMIDES, THEIR PRODUCTION, ANTIMYCOTIC COMPOSITIONS COMPRISING SAID COMPOUNDS AND THEIR USE AS ANTIMYCOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | claimed |
| US-4024270-A | Antimycotic compositions containing an imidazolylacetic acid amide or salt thereof as the active agent and the use thereof in the treatment of mycoses | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | claimed |
| US-3993647-A | ANTIMYCOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | claimed |
| US-3950354-A | ANTIMYCOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240174629-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | OTCPHARM JSC (RU) | 2024-05-30 | — | — | US | disclosed |
| US-3993647-A | ANTIMYCOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3950354-A | ANTIMYCOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3950354-A | ANTIMYCOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |