Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23403253 | 0.90 | TSHR (0.56) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL7518997 | 0.89 | TSHR (0.55) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL11199820 | 0.88 | TSHR (0.53) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL486186 | 0.86 | TSHR (0.61) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5976258 | 0.85 | KDM4E (0.48) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5975036 | 0.84 | ALKBH5 (0.56) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5977431 | 0.84 | KDM4E (0.48) | TSHRKDM4EMAPTLMNAKDM5A | |
| SCHEMBL5975722 | 0.84 | KDM4E (0.47) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5976501 | 0.84 | ALKBH5 (0.51) | TSHRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5975781 | 0.84 | ALKBH5 (0.51) | TSHRKDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35801-E | PYRAZOLONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-05-19 | — | — | US | claimed |
| US-4857542-A | INHIBITOR AGAINST LIPID PEROXIDATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1989-08-15 | — | — | US | claimed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| CN-108997365-B | Series catalytic preparation method of chiral pyrazole spirofuran compound | 浙江工业大学 | 2021-04-06 | — | — | CN | disclosed |
| US-7368224-B2 | High photosensitivity, visible laser recording materials; comprised of novel squarylium compound metal complexes, free radical generators and monomers | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| EP-1334998-B1 | METAL COMPLEX TYPE SQUARYLIUM COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME | KYOWA HAKKO CHEMICAL CO LTD (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-20050164120-A1 | Photopolymerizable composition | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1493757-A1 | PHOTOPOLYMERIZABLE COMPOSITION | Kyowa Hakko Chemical Co., Ltd. (JP) | 2005-01-05 | — | — | EP | disclosed |
| US-6660867-B2 | Squarylium compounds having spectroscopic properties, light resistance, solubility and thermal decomposition properties suitable for a recording material for DVD-R, and optical recording media using the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-20030187272-A1 | Metal complex type squarylium compounds and optical recording media made by using the same | KYOWA HAKKO CHEMICAL CO., LTD. (FORMERLY KYOWA YUKA CO., LTD.) (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1334998-A1 | METAL COMPLEX TYPE SQUARYLIUM COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-4761484-A | PREFERENTIAL EXTRACTION OF COPPER FROM MINERAL CONCENTRATES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0129448-B1 | PROCESS FOR SELECTIVELY EXTRACTING COPPER USING 4-ACYL(3H)-PYRAZOL-3-ONES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-02-10 | — | — | EP | disclosed |
| US-4666513-A | Process for the selective extraction of copper using 4-acyl-(3H)-pyrazol-3-ones | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1987-05-19 | — | — | US | disclosed |
| US-4146540-A | Pyrazole compounds as stabilizers for organic materials | SANDOZ LTD. (CH) | 1979-03-27 | — | — | US | disclosed |
| US-4008200-A | Method of stabilizing organic materials employing pyrazole compounds and stabilized compositions thereof | SANDOZ LTD. (CH) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187272-A1 | Metal complex type squarylium compounds and optical recording media made by using the same | DCLK2, DCLK3, DCLK1 | TSHR 4474/4885KDM4E 1359/4885ALDH1A1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.