SCHEMBL4810185

SCHEMBL4810185

CC/C(=C\c1cccc(C2COc3c(C)c(C)c(NC(=O)CC(C)(C)C)c(C)c32)c1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 2/20 0.34
EPHX2 P34913 1/20 0.33
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4810192 1.00 KCNQ2 (0.34) KCNQ2EPHX2MEN1HPGDKMT2A
SCHEMBL14856319 0.90 TRPV1 (0.33) KCNQ2EPHX2
SCHEMBL14856318 0.90 TRPV1 (0.33) KCNQ2EPHX2
SCHEMBL3602932 0.87 KCNQ2 (0.37) KCNQ2EPHX2MEN1HPGDKMT2A
SCHEMBL3599201 0.85 MEN1 (0.36) KCNQ2MEN1HPGDKMT2A
SCHEMBL3599208 0.85 MEN1 (0.36) KCNQ2MEN1HPGDKMT2A
SCHEMBL3600195 0.83 HPGD (0.40) KCNQ2MEN1HPGDKMT2A
SCHEMBL4810181 0.83 HTT (0.38) KCNQ2HPGD
SCHEMBL3598208 0.80 HPGD (0.34) KCNQ2MEN1HPGDKMT2A
SCHEMBL3603206 0.80 KCNQ2 (0.43) KCNQ2EPHX2MEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465815-B2 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-16 US disclosed
US-20070099990-A1 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099990-A1 Cannabinoid receptor modulator CNR1, CNR2, GPR18 KCNQ2 630/4885EPHX2 1518/4885MEN1 3532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.