Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 15/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810782 | 1.00 | ST14 (0.39) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20075958 | 0.89 | NOS2 (0.38) | — | |
| SCHEMBL1588520 | 0.89 | — | — | |
| Acetic Acid SCHEMBL3959957 | 0.88 | SMYD3 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL1763976 | 0.88 | SMYD3 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL1764210 | 0.88 | SMYD3 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL4900719 | 0.87 | — | — | |
| SCHEMBL26044923 | 0.86 | F2 (0.31) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13998889 | 0.80 | EPHX2 (0.52) | ST14F2 | |
| SCHEMBL10310178 | 0.80 | EPHX2 (0.52) | ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347984-B2 | Mammalian agmatinase inhibitory substance | JACKSON STATE UNIVERSITY (US) | 2008-03-25 | — | — | US | disclosed |
| US-20050220707-A1 | Mammalian agmatinase inhibitory substance | JACKSON STATE UNIVERSITY | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050220707-A1 | Mammalian agmatinase inhibitory substance | ENGASE, DNPEP, GPI | ST14 421/4885F2 2963/4885PRSS1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.