SCHEMBL4811268

SCHEMBL4811268

CC(C)CP1(=O)CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812763 1.00
SCHEMBL14278269 0.97
SCHEMBL4814559 0.72 BLM (0.32)
SCHEMBL4817447 0.72 BLM (0.32)
SCHEMBL4812100 0.70 LMNA (0.36)
SCHEMBL4818356 0.70 LMNA (0.36)
SCHEMBL4810013 0.69 FFAR3 (0.30)
SCHEMBL4818130 0.68
SCHEMBL4813310 0.65
SCHEMBL4808270 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7411096-B2 Process for producing optically active phosphorus heterocyclic dimer NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2008-08-12 US disclosed
US-20060211888-A1 2,2'-bis-(1-alkylphosphetanes); a primary alkyl or cycloalkyl phosphine is reacted with 1,3-dichloropropane, in the presence of n-butyllithium, and then reacted with boron trihydride, oxygen, or sulfur, dimerizing, removing the boron trihydride, oxygen, or sulfur; assymetric hydrogenation catalysts NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2006-09-21 US disclosed
EP-1650216-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE DIMER OF PHOSPHORUS HETEROCYCLE NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) 2006-04-26 EP disclosed