Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954848 | 0.86 | DPP4 (0.39) | DPP4HTR2CTSHRENPP2JAK2 | |
| SCHEMBL953150 | 0.86 | DPP4 (0.39) | DPP4HTR2CTSHRENPP2JAK2 | |
| SCHEMBL953151 | 0.86 | DPP4 (0.39) | DPP4HTR2CTSHRENPP2JAK2 | |
| SCHEMBL8206794 | 0.86 | DPP4 (0.39) | DPP4HTR2CTSHRENPP2JAK2 | |
| SCHEMBL4340453 | 0.85 | TSHR (0.52) | DPP4HTR2CTSHRPLD1PSEN1 | |
| Hydrochloric Acid SCHEMBL17560459 | 0.84 | DPP4 (0.38) | DPP4HTR2CTSHRENPP2JAK2 | |
| Hydrochloric Acid SCHEMBL17560457 | 0.84 | DPP4 (0.38) | DPP4HTR2CTSHRENPP2JAK2 | |
| Hydrochloric Acid SCHEMBL17560440 | 0.84 | TSHR (0.50) | DPP4HTR2CTSHRPLD1PSEN1 | |
| Hydrochloric Acid SCHEMBL17560424 | 0.84 | TSHR (0.50) | DPP4HTR2CTSHRPLD1PSEN1 | |
| Hydrochloric Acid SCHEMBL17560448 | 0.84 | TSHR (0.50) | DPP4HTR2CTSHRPLD1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |