Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953150 | 1.00 | DPP4 (0.39) | DPP4MAPTHTR2CGAAJAK2 | |
| SCHEMBL954848 | 1.00 | DPP4 (0.39) | DPP4MAPTHTR2CGAAJAK2 | |
| SCHEMBL953151 | 1.00 | DPP4 (0.39) | DPP4MAPTHTR2CGAAJAK2 | |
| Hydrochloric Acid SCHEMBL17560459 | 0.98 | DPP4 (0.38) | DPP4MAPTHTR2CGAAJAK2 | |
| Hydrochloric Acid SCHEMBL17560457 | 0.98 | DPP4 (0.38) | DPP4MAPTHTR2CGAAJAK2 | |
| SCHEMBL18705721 | 0.89 | DPP4 (0.37) | DPP4MAPTHTR2CJAK2JAK1 | |
| SCHEMBL18705711 | 0.89 | DPP4 (0.37) | DPP4MAPTHTR2CJAK2JAK1 | |
| SCHEMBL18705712 | 0.89 | DPP4 (0.37) | DPP4MAPTHTR2CJAK2JAK1 | |
| SCHEMBL572253 | 0.86 | LMNA (0.43) | DPP4HTR2CTSHRALDH1A1LMNA | |
| SCHEMBL13486466 | 0.86 | LMNA (0.43) | DPP4HTR2CTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114531-A | Process for preparing quinolone and naphthyridone carboxylic acids | PFIZER INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0976749-A1 | Process for preparing quinolone and naphthyridone carboxylic acids | Pfizer Products Inc. (US) | 2000-02-02 | — | — | EP | disclosed |