Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346759 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9343393 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8992393 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9345797 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9346808 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9343386 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9346749 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9341889 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4811839 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9405689 | 1.00 | RARB (0.44) | RARBMAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399505-B2 | Fluorinated phenanthrenes and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2008-07-15 | — | — | US | disclosed |
| US-7297378-B2 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-7282246-B2 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-10-16 | — | — | US | disclosed |
| US-7255900-B2 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7195719-B1 | High polarization ferroelectric liquid crystal compositions | DISPLAYTECH, INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-7026021-B2 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-7018685-B2 | Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2006-03-28 | — | — | US | disclosed |
| US-20050274929-A1 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
| US-20050258400-A1 | Fluorinated phenanthrenes and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| WO-1990013611-A2 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |
| EP-0373191-A1 | HETEROCYCLIC 1,2-DIFLUOROBENZENE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0362317-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK PATENT GmbH (DE) | 1990-04-11 | — | — | EP | disclosed |
| EP-0357739-A1 | CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE | MERCK PATENT GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989008690-A1 | SMECTIC LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008649-A1 | HETEROCYCLIC 1,2-DIFLUOROBENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008639-A1 | CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332024-A1 | Heterocyclic derivatives of 1,2-difluorobenzene | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0332025-A1 | Chiral derivatives of 1,2-difluorobenzenes | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0332006-A1 | Smectic liquid-crystal composition | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050274929-A1 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | CHRM1, HAX1, CHRM2 | RARB 1995/4885MAPT 3543/4885RAB9A 1554/4885 |
| US-20050258400-A1 | Fluorinated phenanthrenes and their use in liquid-crystal mixtures | CHRM1, AFF1, F2 | RARB 2801/4885MAPT 3438/4885RAB9A 3039/4885 |
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | CHRM1, AFF1, H1-0 | RARB 2236/4885MAPT 3564/4885RAB9A 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.