Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.72 |
| ▸ | CTSL | P07711 | 5/20 | 0.65 |
| ▸ | CTSS | P25774 | 5/20 | 0.65 |
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | CTSH | P09668 | 1/20 | 0.65 |
| ▸ | CTSV | O60911 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813617 | 1.00 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL5637804 | 1.00 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL4813599 | 1.00 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL4819313 | 0.82 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL4819332 | 0.82 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL15237928 | 0.81 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14943214 | 0.81 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL12487120 | 0.80 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL10255250 | 0.77 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSH | |
| SCHEMBL13350503 | 0.77 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402606-B2 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-22 | — | — | US | claimed |