SCHEMBL4813742

SCHEMBL4813742

COCCCOc1cc(CC(CC(NC(=O)OC(C)OC(=O)C(C)C)C(O)CC(C(=O)NC2CCOCC2)C(C)C)C(C)C)ccc1OC

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813740 1.00 REN (0.54) REN
SCHEMBL8476036 1.00 REN (0.54) REN
SCHEMBL4754605 0.91 REN (0.55) REN
SCHEMBL4754608 0.91 REN (0.55) REN
SCHEMBL8469021 0.87 REN (0.61) REN
SCHEMBL8471482 0.84 REN (0.56) REN
SCHEMBL427814 0.84 REN (0.71) REN
SCHEMBL4641022 0.84 REN (0.51) REN
SCHEMBL4818254 0.83 REN (0.39) REN
SCHEMBL4818258 0.83 REN (0.39) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911762-A1 Amino alcohols and their use as renin inhibitors Speedel Experimenta AG (CH) 2008-04-16 EP disclosed