Butadiene

Butadiene

SCHEMBL4814860

C=CC=C.C=CC=CC(=C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438836 0.97
SCHEMBL1000736 0.97
SCHEMBL13663854 0.97
Butadiene SCHEMBL8752736 0.94 ALDH1A1 (0.56) ALDH1A1TP53TSHR
SCHEMBL28854466 0.88 ALDH1A1 (0.40) ALDH1A1TP53TSHR
SCHEMBL21571918 0.86 ALDH1A1 (0.38) ALDH1A1TP53TSHR
SCHEMBL5618703 0.85
SCHEMBL19202510 0.85
SCHEMBL29405666 0.79 ALDH1A1 (0.47) ALDH1A1TP53TSHR
SCHEMBL29795040 0.79 ALDH1A1 (0.47) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7429549-B2 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-09-30 US disclosed
US-7153920-B2 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2006-12-26 US disclosed
EP-1359165-B1 Synthesis of high vinyl rubber GOODYEAR TIRE & RUBBER (US) 2006-11-15 EP disclosed
US-7074869-B2 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-07-11 US disclosed
US-7064171-B1 Non-random styrene-butadiene rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-20 US disclosed
US-20050256284-A1 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2005-11-17 US disclosed
US-6867265-B2 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-15 US disclosed
US-20050049141-A1 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY. 2005-03-03 US disclosed
US-20040127659-A1 Synthesis of functionalized high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY 2004-07-01 US disclosed
EP-1359165-A1 Synthesis of high vinyl rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-11-05 EP disclosed
EP-0884360-A1 Technique for reducing the cold flow of rubbers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-12-16 EP disclosed
US-5686530-A BUTADIENE-ISOPRENE DIBLOCK POLYMER BLEND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-11-11 US disclosed
US-5677402-A USING A ORGANOLITHIUM PROMOTER AND SODIUM ALKOXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-14 US disclosed
EP-0796898-A1 Tire tread compound THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-24 EP disclosed
US-5654384-A USING AN LITHIUM INITIATOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-08-05 US disclosed
US-5620939-A Initiative system THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-04-15 US disclosed
EP-0764688-A1 High performance blend for tire treads THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-26 EP disclosed
US-5612436-A PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-18 US disclosed
EP-0761703-A1 Isoprene-butadiene diblock rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-12 EP disclosed
US-5534592-A POLYBUTADIENE RUBBER BLEND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-07-09 US disclosed