SCHEMBL4815215

SCHEMBL4815215

CCOC(=O)C1(c2ccc(C)cc2)CCCC1OC(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 1/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
HTR2C P28335 1/20 0.41
OPRM1 P35372 3/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ADAM17 P78536 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813759 0.96 SLC22A1 (0.46) SLC22A1KMT2AHTR2COPRM1OPRD1
SCHEMBL4815535 0.94 OPRM1 (0.43) SLC22A1KMT2AMAPTHTR2COPRM1
SCHEMBL4808103 0.90 NPSR1 (0.39) SLC22A1KMT2AMAPTCRHBPCRHR2
SCHEMBL4813911 0.90 HTR2C (0.46) KMT2AHTR2CMEN1TDP1
SCHEMBL4810621 0.89 HTR2C (0.39) SLC22A1KMT2AMAPTCRHBPCRHR2
SCHEMBL4810643 0.88 SLC22A1 (0.43) SLC22A1MAPTOPRM1OPRD1OPRK1
SCHEMBL4810288 0.87 SLC22A1 (0.40) SLC22A1KMT2AHTR2COPRM1OPRD1
SCHEMBL4810480 0.85 PLA2G1B (0.39) SLC22A1KMT2AMAPTHTR2COPRM1
SCHEMBL4808284 0.85 HTR2C (0.46) KMT2AMAPTHTR2CMEN1TDP1
SCHEMBL4809674 0.85 OPRM1 (0.44) SLC22A1KMT2AHTR2COPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7388103-B2 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
CN-100338018-C Cyclopentyl ester analog compound and its synthesis method and uses CHINA PETROLEUM & CHEMICAL (CN) 2007-09-19 CN disclosed
US-20060094843-A1 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 US disclosed
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed
CN-1765871-A Cyclopentyl ester analog compound and its synthesis method and uses CHINA PETROLEUM & CHEMICAL (CN) 2006-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094843-A1 Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof C5, C1S, AKR1C3 SLC22A1 3001/4885KMT2A 4572/4885MAPT 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.