Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695388 | 0.81 | OPRL1 (0.59) | OPRL1MCHR1CAPN1 | |
| Trifluoroacetic Acid SCHEMBL4900055 | 0.80 | OPRL1 (0.56) | OPRL1CAPN1 | |
| SCHEMBL4900181 | 0.79 | OPRL1 (0.56) | OPRL1MCHR1CAPN1 | |
| SCHEMBL4933523 | 0.78 | OPRL1 (0.73) | OPRL1MCHR1CAPN1 | |
| SCHEMBL4900056 | 0.75 | OPRL1 (0.54) | OPRL1CAPN1 | |
| Citric Acid SCHEMBL4943418 | 0.75 | OPRL1 (0.64) | OPRL1MCHR1 | |
| SCHEMBL4977721 | 0.72 | OPRL1 (0.82) | OPRL1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4981881 | 0.70 | OPRL1 (0.77) | OPRL1MCHR1 | |
| SCHEMBL4888999 | 0.70 | OPRL1 (0.46) | OPRL1CAPN1 | |
| Trifluoroacetic Acid SCHEMBL4898487 | 0.70 | OPRL1 (0.44) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896479-A1 | ALPHA-(ARYL-OR HETEROARYL-METHYL)-BETA-PIPERIDINOPROPANOIC ACID COMPOUNDS AS ORL1-RECEPTOR ANTAGONISTS | Pfizer, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006134485-A1 | ALPHA-(ARYL-OR HETEROARYL-METHYL)-BETA-PIPERIDINOPROPANOIC ACID COMPOUNDS AS ORL1-RECEPTOR ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-12-21 | — | — | WO | disclosed |