Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888999 | 0.95 | OPRL1 (0.46) | OPRL1AVPR1AOPRD1 | |
| Trifluoroacetic Acid SCHEMBL4900055 | 0.91 | OPRL1 (0.56) | OPRL1AVPR1A | |
| SCHEMBL4898494 | 0.89 | OPRL1 (0.43) | OPRL1AVPR1AOPRD1CTSBCTSS | |
| SCHEMBL4695388 | 0.86 | OPRL1 (0.59) | OPRL1 | |
| SCHEMBL4936147 | 0.86 | OPRL1 (0.57) | OPRL1AVPR1AOPRD1 | |
| SCHEMBL4797089 | 0.85 | OPRL1 (0.43) | OPRL1AVPR1A | |
| Trifluoroacetic Acid SCHEMBL4976084 | 0.84 | OPRL1 (0.62) | OPRL1AVPR1A | |
| Citric Acid SCHEMBL4932703 | 0.84 | OPRL1 (0.51) | OPRL1AVPR1AOPRD1 | |
| SCHEMBL4900056 | 0.80 | OPRL1 (0.54) | OPRL1 | |
| SCHEMBL4976662 | 0.79 | OPRL1 (0.65) | OPRL1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207665-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidinopropanoic Acid Compounds as Orl-1-Receptor Antagonists | PFIZER INC. | 2008-08-28 | — | — | US | disclosed |
| US-20080200490-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidino Propanamide Compounds as Orl-1-Receptor Antagonists | PFIZER INC. | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200490-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidino Propanamide Compounds as Orl-1-Receptor Antagonists | OPRL1, OPRD1, OGFRL1 | OPRL1 1/4885AVPR1A 236/4885AGTR2 178/4885 |
| US-20080207665-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidinopropanoic Acid Compounds as Orl-1-Receptor Antagonists | OPRL1, OGFRL1, OPRD1 | OPRL1 1/4885AVPR1A 464/4885AGTR2 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.