SCHEMBL4815634

SCHEMBL4815634

CCCS(=O)(=O)c1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4811896 0.88 TRPV1 (0.67) TRPV1
SCHEMBL4811324 0.87 TRPV1 (0.68) TRPV1
SCHEMBL4813597 0.87 TRPV1 (0.65) TRPV1
SCHEMBL14252856 0.87 TRPV1 (0.76) TRPV1
SCHEMBL4811321 0.85 TRPV1 (0.75) TRPV1
SCHEMBL4811455 0.85 TRPV1 (0.65) TRPV1
SCHEMBL14263322 0.85 TRPV1 (0.76) TRPV1
SCHEMBL4815621 0.84 TRPV1 (0.72) TRPV1
SCHEMBL14084061 0.84 TRPV1 (0.72) TRPV1
SCHEMBL14252869 0.84 TRPV1 (0.72) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7338950-B2 Amide compounds as ion channel ligands and uses thereof RENOVIS, INC. (US) 2008-03-04 — — US disclosed
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