Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815634 | 0.88 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4815483 | 0.86 | TRPV1 (0.51) | TRPV1CA12CA1CA9DEGS1 | |
| SCHEMBL4811888 | 0.85 | TRPV1 (0.70) | TRPV1SCN5ASCN9ADEGS1 | |
| SCHEMBL15779639 | 0.81 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL4464126 | 0.81 | TRPV1 (1.00) | TRPV1DEGS1 | |
| SCHEMBL10324365 | 0.80 | TRPV1 (0.78) | TRPV1SCN5ASCN9ADEGS1 | |
| SCHEMBL14084066 | 0.79 | TRPV1 (0.80) | TRPV1SCN5ASCN9ADEGS1 | |
| SCHEMBL14252856 | 0.76 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL4811324 | 0.76 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL4811321 | 0.75 | TRPV1 (0.75) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |