Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 7/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815827 | 1.00 | DGAT1 (0.54) | DGAT1SOAT1HRH3EPHX2FAAH | |
| SCHEMBL4808228 | 0.89 | DGAT1 (0.51) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4808208 | 0.89 | DGAT1 (0.51) | DGAT1SOAT1DGAT2 | |
| SCHEMBL3545265 | 0.86 | DGAT1 (0.66) | DGAT1SOAT1HRH3 | |
| SCHEMBL3545268 | 0.86 | DGAT1 (0.66) | DGAT1SOAT1HRH3 | |
| SCHEMBL3540413 | 0.84 | DGAT1 (0.71) | DGAT1SOAT1DGAT2 | |
| SCHEMBL3540414 | 0.84 | DGAT1 (0.71) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4883330 | 0.84 | DGAT1 (0.70) | DGAT1SOAT1DGAT2 | |
| SCHEMBL4883344 | 0.84 | DGAT1 (0.70) | DGAT1SOAT1DGAT2 | |
| SCHEMBL5306102 | 0.84 | DGAT1 (0.52) | DGAT1SOAT1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129319-A1 | SALTS OF OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |