Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474241 | 0.87 | KCNH3 (0.47) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL969407 | 0.84 | MAPT (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30726074 | 0.81 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9781825 | 0.80 | CYP1A2 (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11269588 | 0.80 | MAPT (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8373327 | 0.79 | MAPT (1.00) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29612398 | 0.79 | MAPT (0.75) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9396667 | 0.79 | MAPT (0.75) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7650570 | 0.78 | HPGD (0.46) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4816942 | 0.78 | GRM5 (0.51) | MAPTCYP3A4HTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104973999-A | Novel method for preparing allene by cesium hydroxide catalysis | UNIV HUNAN | 2015-10-14 | — | — | CN | claimed |
| CN-104973999-A | Novel method for preparing allene by cesium hydroxide catalysis | UNIV HUNAN | 2015-10-14 | — | — | CN | disclosed |
| EP-1740579-B1 | TRICYCLIC PYRAZOLE KINASE INHIBITORS | ABBVIE INC (US) | 2015-08-19 | — | — | EP | disclosed |
| US-7468371-B2 | Tricyclic pyrazole kinase inhibitors | ABBOTT LABORATORIES INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060014816-A1 | Tricyclic pyrazole kinase inhibitors | ABBVIE INC. | 2006-01-19 | — | — | US | disclosed |
| EP-0161480-B1 | N-IODINE PROPARGYL-CHLOROMETHANESULFONAMIDE | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0161480-A1 | N-iodine propargyl-chloromethanesulfonamide | BAYER AG (DE) | 1985-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014816-A1 | Tricyclic pyrazole kinase inhibitors | PRKDC, PRKACA, PIK3C3 | MAPT 2427/4885CYP1A2 2708/4885CYP3A4 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.