SCHEMBL4816014

SCHEMBL4816014

O=C(O)CNCC(=O)O.O=C(O)CNCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
EGLN1 Q9GZT9 3/20 0.50
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.44
TSHR P16473 2/20 0.41
NFKB1 P19838 1/20 0.41
PMP22 Q01453 1/20 0.41
CTH P32929 1/20 0.41
KDM4E B2RXH2 2/20 0.40
KDM5C P41229 2/20 0.40
PHF8 Q9UPP1 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
KDM6B O15054 1/20 0.40
FOLH1 Q04609 1/20 0.40
FFAR3 O14843 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27023 1.00
Ammonia Solution, Strong SCHEMBL7262619 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
SCHEMBL10627876 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
SCHEMBL667660 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
Water SCHEMBL11785760 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
Water SCHEMBL9703549 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
SCHEMBL3464176 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
SCHEMBL4015593 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
Ammonia Solution, Strong SCHEMBL7262621 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5
SCHEMBL9393647 0.96 LMNA (0.47) LMNAEGLN1LDHASRRALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617131-B1 Reagent for determining gamma-glutamyl transpeptidase EIKEN CHEMICAL (JP) 1998-11-04 EP claimed
US-5783169-A RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 1998-07-21 US claimed
US-7438405-B2 Ink set for ink jet recording, ink jet recording method, and ink jet recording apparatus FUJI XEROX CO., LTD. (JP) 2008-10-21 US disclosed
US-20040257420-A1 Ink set for ink jet recording, ink jet recording method, and ink jet recording apparatus FUJI XEROX CO., LTD. (JP) 2004-12-23 US disclosed
EP-0876161-B1 CONTRAST MEDIA NYCOMED SALUTAR INC (US) 2001-11-21 EP disclosed
EP-0876161-A2 CONTRAST MEDIA NYCOMED SALUTAR, INC. (US) 1998-11-11 EP disclosed
US-5783169-A RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 1998-07-21 US disclosed
US-5783169-A RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 1998-07-21 US disclosed
WO-1997026921-A2 CONTRAST MEDIA NYCOMED SALUTAR INC. (US) 1997-07-31 WO disclosed
EP-0548217-A1 PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES. BUCHARDT OLE (DK) 1993-06-30 EP disclosed
US-4396707-A STABILIZERS AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
US-4366231-A Photographic material containing a stabilizer, a process for its production, a development process, new pyrazoles, a process for their production and intermediate products AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed