SCHEMBL4816502

SCHEMBL4816502

NC(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PYGB P11216 7/20 0.65
GAA P10253 1/20 0.65
CA1 P00915 6/20 0.57
CA2 P00918 6/20 0.57
CA9 Q16790 6/20 0.57
CA12 O43570 3/20 0.57
AKR1B1 P15121 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28491648 1.00 PYGB (0.65) PYGBGAACA1CA2CA9
SCHEMBL10939188 1.00 PYGB (0.65) PYGBGAACA1CA2CA9
SCHEMBL1208980 0.98 PYGB (0.62) PYGBGAACA1CA2CA9
SCHEMBL22195972 0.98 PYGB (0.62) PYGBGAACA1CA2CA9
SCHEMBL1208976 0.98 PYGB (0.62) PYGBGAACA1CA2CA9
SCHEMBL30957909 0.85 PYGB (0.69) PYGBGAACA1CA2CA9
SCHEMBL30498599 0.84 CA12 (0.57) PYGBGAACA1CA2CA9
SCHEMBL29977113 0.84 CA12 (0.57) PYGBGAACA1CA2CA9
SCHEMBL9343539 0.83 PYGB (0.67) PYGBGAACA1CA2CA9
SCHEMBL13745906 0.83 PYGB (0.77) PYGBGAACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP claimed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP disclosed
US-7381540-B2 Composition for measuring glucose having improved substrate specificity TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-06-03 US disclosed
US-20070037239-A1 Lowering reactivity on maltose by reacting modified pyrroloquinoline quinone dependent glucose dehydrogenase with succinic, malonic, glutaric, malic acid and ferricyanide salt TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-02-15 US disclosed
EP-1752769-A1 Composition for measuring glucose having improved substrate specificity Toyo Boseki Kabushiki Kaisha (JP) 2007-02-14 EP disclosed
JP-2003261591-A LYOPHILIZATION STABILIZER HAYADE KOJI 2003-09-19 JP disclosed
EP-0062329-A1 Novel nitrosourea derivative, process for preparing same and therapeutic composition containing said derivate Tanabe Seiyaku Co., Ltd. (JP) 1982-10-13 EP disclosed