Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564029 | 0.98 | TLR7 (0.59) | TLR7PDE4DPOLBHTR2AHTR2B | |
| SCHEMBL29379266 | 0.98 | TLR7 (0.59) | TLR7PDE4DPOLBHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL5435065 | 0.97 | TLR7 (0.58) | TLR7PDE4DPOLBHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL9602331 | 0.96 | TLR7 (0.56) | TLR7PDE4DPOLBHTR2AHTR2B | |
| Propionic Acid SCHEMBL6726633 | 0.88 | TLR7 (0.53) | TLR7PDE4DPOLBHTR2AHTR2B | |
| SCHEMBL10734092 | 0.88 | TLR7 (0.50) | TLR7PDE4DPOLBHTR2AHTR2B | |
| SCHEMBL10727888 | 0.87 | TLR7 (0.47) | TLR7PDE4DPOLBHTR2AHTR2B | |
| Sarcosine SCHEMBL3196280 | 0.85 | TLR7 (0.50) | TLR7PDE4DPOLBHTR2AHTR2B | |
| Toluic Acid SCHEMBL6723514 | 0.83 | TLR7 (0.48) | TLR7PDE4DPOLBHTR2AHTR2B | |
| SCHEMBL9601955 | 0.81 | SMN1; SMN2 (0.42) | TLR7PDE4DPOLBHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100372847-C | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via novel 1H-imidazo [4,5-C] quinolin-4-cyano and 1H-imidazo [4,5-C] quinolin-4-carboxamide intermediates | TEVA PHARMA (HU) | 2008-03-05 | — | — | CN | disclosed |
| US-7335772-B2 | 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2008-02-26 | — | — | US | disclosed |
| US-7335772-B2 | 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2008-02-26 | — | — | US | disclosed |
| US-7166721-B2 | Preparation of 1H-imidazo[4,5-C] quinolin 4-amines via novel 1H-imidazo[4,5-c] quinolin 4-cyano and 1H-imidazo[4,5-c] quinolin 4-carboxamide intermediates | TEVA Gyógyszergyár Zártkörűen Működő Részvénytársaság (HU) | 2007-01-23 | — | — | US | disclosed |
| US-7153967-B2 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2006-12-26 | — | — | US | disclosed |
| CN-1684963-A | Preparation of 1H-imidazo [4, 5-C ] quinolin-4-amines via novel 1H-imidazo [4, 5-C ] quinolin-4-cyano and 1H-imidazo [4, 5-C ] quinolin-4-carboxamide intermediates | TEVA PHARMA (HU) | 2005-10-19 | — | — | CN | disclosed |
| US-20050119294-A1 | Preparation of 1H-imidazo [4,5-c] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | BIOGAL GYOGYSZERGYAR RT. | 2005-06-02 | — | — | US | disclosed |
| US-20050119294-A1 | Preparation of 1H-imidazo [4,5-c] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | BIOGAL GYOGYSZERGYAR RT. | 2005-06-02 | — | — | US | disclosed |
| US-20050113404-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | BIOGAL GYOGYSZERGYAR RT. | 2005-05-26 | — | — | US | disclosed |
| US-20050101627-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4 amines via novel 1h-imidazo [4,5-C] quinolin-4-cyano and 1h-imidazo [4,5-C] quinolin-4-carboxamide intermediates | TEVA PHARAMCEUTICAL INDUSTRIES LTD TO BIOGAL GYOGYSZERGYAR RT. | 2005-05-12 | — | — | US | disclosed |
| US-20050101627-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4 amines via novel 1h-imidazo [4,5-C] quinolin-4-cyano and 1h-imidazo [4,5-C] quinolin-4-carboxamide intermediates | TEVA PHARAMCEUTICAL INDUSTRIES LTD TO BIOGAL GYOGYSZERGYAR RT. | 2005-05-12 | — | — | US | disclosed |
| US-6852861-B2 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-02-08 | — | — | US | disclosed |
| US-20040138459-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101627-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4 amines via novel 1h-imidazo [4,5-C] quinolin-4-cyano and 1h-imidazo [4,5-C] quinolin-4-carboxamide intermediates | KDM4C, P2RX4, IL4 | TLR7 4/4885PDE4D 578/4885POLB 1589/4885 |
| US-20050113404-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TLR7, IL4, P2RY4 | TLR7 1/4885PDE4D 458/4885POLB 1630/4885 |
| US-20040138459-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TLR7, IL4, P2RY4 | TLR7 1/4885PDE4D 458/4885POLB 1630/4885 |
| US-20050119294-A1 | Preparation of 1H-imidazo [4,5-c] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | KDM4C, IFNAR1, P2RX4 | TLR7 8/4885PDE4D 559/4885POLB 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.