SCHEMBL4818635

SCHEMBL4818635

O=C(O)C1CCCC[C@H]1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MEN1 O00255 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
GRM4 Q14833 1/20 0.47
KDM4E B2RXH2 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20680 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL1805083 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL38660911 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL150816 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL1680973 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL2515289 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL150817 1.00 PEPD (0.54) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL23573909 0.97 PEPD (0.52) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL1964404 0.97 PEPD (0.52) PEPDALDH1A1LMNAMEN1BLM
SCHEMBL20603957 0.97 PEPD (0.52) PEPDALDH1A1LMNAMEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115725064-B Preparation method of polycarbonate with main chain containing parallel ring structure 四川大学 2024-04-12 CN disclosed
CN-117285530-A New preparation method of lurasidone hydrochloride 迪嘉药业集团股份有限公司 2023-12-26 CN disclosed
CN-115725064-A Preparation method of polycarbonate with main chain containing parallel-ring structure 四川大学 2023-03-03 CN disclosed
EP-3854471-A1 IMPROVEMENTS RELATING TO WATER PURIFICATION Molecule RND Limited (IE) 2021-07-28 EP disclosed
WO-2020021112-A1 IMPROVEMENTS RELATING TO WATER CAPTURE UNIVERSITY OF LIMERICK (IE) 2020-01-30 WO disclosed
WO-2016085634-A1 PROCESS FOR EXTRUDING POLYPROPYLENE MILLIKEN & COMPANY (US) 2016-06-02 WO disclosed
WO-2016085633-A1 PROCESS FOR EXTRUDING POLYPROPYLENE MILLIKEN & COMPANY (US) 2016-06-02 WO disclosed
WO-2014102808-A1 A PROCESS FOR PREPARATION OF TRANS (LR,2R)-CYCLO HEXANE 1, 2-DICARBOXYLIC ACID LEE PHARMA LIMITED (IN) 2014-07-03 WO disclosed
US-8735582-B2 Method for producing carboxylic anhydride and arylboronic acid compound NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-05-27 US disclosed
US-20110319620-A1 METHOD FOR PRODUCING CARBOXYLIC ANHYDRIDE AND ARYLBORONIC ACID COMPOUND NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2011-12-29 US disclosed
WO-2009001128-A1 1,2-CYCL0HEXANE DICARBOXAMIDES AS CATHEPSIN INHIBITORS ASTRAZENECA AB (SE) 2008-12-31 WO disclosed
US-6995177-B1 HCV NS3 protease inhibitors ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) 2006-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319620-A1 METHOD FOR PRODUCING CARBOXYLIC ANHYDRIDE AND ARYLBORONIC ACID COMPOUND CA6, CA9, APEH PEPD 264/4885ALDH1A1 195/4885LMNA 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.